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  1. Instead of stacking multiple 4066/4016 quad analog switches for additional channels, it might make more sense to use 2:1, 4:1 or 8:1 mux chips. This would certainly require fewer redundant connections. Candidates would be the 4353/4053 2:1, 4852/4052 4:1, or even the 4351/4051 8:1 mux.

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