It would be pretty nice/easy to do differential measurements in hardware so you don't have to store both samples, yes?
And off the top of my head crazyness...
This is probably a ridiculous idea, but all this talk of high speed ADC makes me think if a v2 of SUMP ever shows up, it might be a worthwhile target to try to implement basically half of the gnu universal software radio. (Cypress EZ-USB High speed, FPGA, single AD9862 [or just a 12bit ADC-only rather than codec, and could be on a header rather than installed, as with a DSO ADC/frontend], and USRP-compatible header for the peripherals.) It would be interesting to see at least how close you could get for rather less than the $700 the USRP costs.
My guess is you could make a single board that could do buffered logic analysis as well as optional DSO/software radio receiver upgrades for a fraction of the cost. But maybe the market is too limited for that. :)